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Received 2010 Sep 1; Accepted 2010 Sep 27; Issue date 2010 Dec.

. The National Health System in the UK has evolved to turn into one of the biggest health care systems in the world. At the time of writing of this evaluation (August 2010) the UK government in its 2010 White Paper "Equity and quality: Liberating the NHS" has revealed a method on how it will "develop a more responsive, patient-centred NHS which accomplishes outcomes that are amongst the very best worldwide". This evaluation post presents a summary of the UK healthcare system as it currently stands, with emphasis on Predictive, Preventive and Personalised Medicine elements. It aims to work as the basis for future EPMA articles to expand on and present the changes that will be executed within the NHS in the forthcoming months.
Keywords: UK, Healthcare system, National health system, NHS
Introduction
The UK healthcare system, National Health Service (NHS), came into existence in the aftermath of the Second World War and became operational on the fifth July 1948. It was first proposed to the Parliament in the 1942 Beveridge Report on Social Insurance and Allied Services and it is the tradition of Aneurin Bevan, a previous miner who became a political leader and the then Minister of Health. He founded the NHS under the concepts of universality, complimentary at the point of delivery, equity, and paid for by central funding [1] Despite numerous political and organisational modifications the NHS remains to date a service readily available widely that takes care of individuals on the basis of need and not capability to pay, and which is funded by taxes and nationwide insurance coverage contributions.
Healthcare and health policy for England is the obligation of the main federal government, whereas in Scotland, Wales and Northern Ireland it is the obligation of the respective devolved governments. In each of the UK nations the NHS has its own unique structure and organisation, but in general, and not dissimilarly to other health systems, health care consists of two broad areas; one handling strategy, policy and management, and the other with real medical/clinical care which remains in turn divided into main (community care, GPs, Dentists, Pharmacists and so on), secondary (hospital-based care accessed through GP recommendation) and tertiary care (specialist healthcare facilities). Increasingly distinctions between the two broad areas are becoming less clear. Particularly over the last years and directed by the "Shifting the Balance of Power: The Next Steps" (2002) and "Wanless" (2004) reports, progressive modifications in the NHS have actually led to a higher shift towards local instead of main choice making, elimination of barriers in between main and secondary care and more powerful focus on patient choice [2, 3] In 2008 the previous federal government enhanced this direction in its health strategy "NHS Next Stage Review: High Quality Care for All" (the Darzi Review), and in 2010 the existing government's health technique, "Equity and excellence: Liberating the NHS", remains supportive of the same ideas, albeit through perhaps different mechanisms [4, 5]
The UK government has actually just revealed plans that according to some will produce the most extreme modification in the NHS since its inception. In the 12th July 2010 White Paper "Equity and excellence: Liberating the NHS", the current Conservative-Liberal Democrat coalition federal government laid out a strategy on how it will "create a more responsive, patient-centred NHS which achieves outcomes that are among the very best on the planet" [5]
This review short article will therefore present a summary of the UK health care system as it presently stands with the goal to act as the basis for future EPMA posts to expand and provide the changes that will be implemented within the NHS in the forthcoming months.
The NHS in 2010
The Health Act 2009 developed the "NHS Constitution" which formally brings together the purpose and concepts of the NHS in England, its values, as they have been established by clients, public and staff and the rights, pledges and obligations of patients, public and staff [6] Scotland, Northern Ireland and Wales have likewise consented to a high level statement stating the concepts of the NHS across the UK, even though services might be offered differently in the four nations, showing their different health requirements and circumstances.
The NHS is the biggest employer in the UK with over 1.3 million personnel and a spending plan of over ₤ 90 billion [7, 8] In 2008 the NHS in England alone used 132,662 medical professionals, a 4% increase on the previous year, and 408,160 nursing personnel (Table 1). Interestingly the Kings Fund estimates that, while the overall number of NHS staff increased by around 35% between 1999 and 2009, over the very same period the number of managers increased by 82%. As a proportion of NHS staff, the variety of supervisors rose from 2.7 percent in 1999 to 3.6 per cent in 2009 (www.kingsfund.org.uk). In 2007/8, the UK health costs was 8.5% of Gross Domestic Product (GDP)-with 7.3% accounting for public and 1.2% for personal costs. The net NHS expense per head across the UK was most affordable in England (₤ 1,676) and greatest in Scotland (₤ 1,919) with Wales and Northern Ireland at around the very same level (₤ 1,758 and ₤ 1,770, respectively) [8]
Table 1.

The circulation of NHS workforce according to primary personnel groups in the UK in 2008 (NHS Information Centre: www.ic.nhs.uk)
The general organisational structure of the NHS in England, Scotland, Wales and Northern Ireland in 2010 is displayed in Fig. 1. In England the Department of Health is accountable for the direction of the NHS, social care and public health and delivery of healthcare by establishing policies and methods, protecting resources, monitoring performance and setting nationwide requirements [9] Currently, 10 Strategic Health Authorities manage the NHS at a regional level, and Primary Care Trusts (PCTs), which currently control 80% of the NHS' budget plan, offer governance and commission services, in addition to guarantee the availability of services for public heath care, and arrangement of neighborhood services. Both, SHAs and PCTs will cease to exist once the plans detailed in the 2010 White Paper end up being carried out (see section listed below). NHS Trusts operate on a "payment by outcomes" basis and acquire most of their earnings by offering health care that has actually been commissioned by the practice-based commissioners (GPs, etc) and PCTs. The primary types of Trusts consist of Acute, Care, Mental Health, Ambulance, Children's and Foundation Trusts. The latter were created as non-profit making entities, free of government control however likewise increased financial obligations and are managed by an independent Monitor. The Care Quality Commission manages individually health and adult social care in England in general. Other expert bodies offer monetary (e.g. Audit Commission, National Audit Office), treatment/services (e.g. National Patient Safety Agency, Medicines and Healthcare Products Regulatory Agency) and professional (e.g. British Medical Association) regulation. The National Institute for Health and Clinical Excellence (NICE) was developed in 1999 as the body accountable for developing national standards and standards related to, health promo and avoidance, assessment of new and existing innovation (including medications and procedures) and treatment and care scientific assistance, readily available throughout the NHS. The health research study method of the NHS is being executed through National Institute of Health Research (NIHR), the overall budget for which was in 2009/10 near to ₤ 1 billion (www.nihr.ac.uk) [10]
Fig. 1.
Organisation of the NHS in England, Scotland, Wales and Northern Ireland, in 2010
Section 242 of the NHS Act specifies that Trusts have a legal task to engage and include patients and the general public. Patient experience information/feedback is formally gathered nationally by yearly survey (by the Picker Institute) and is part of the NHS Acute Trust efficiency framework. The Patient Advice Liaison Service (PALS) and Local Involvement Networks (LINks) support patient feedback and participation. Overall, inpatients and outpatients studies have revealed that patients rate the care they receive in the NHS high and around three-quarters show that care has been excellent or exceptional [11]
In Scotland, NHS Boards have actually replaced Trusts and supply an integrated system for strategic instructions, performance management and clinical governance, whereas in Wales, the National Delivery Group, with guidance from the National Advisory Board, is the body performing these functions (www.show.scot.nhs.uk; www.wales.nhs.uk). Scottish NHS and Special Boards deliver services, with look after particular conditions delivered through Managed Clinical Networks. Clinical standards are published by the Scottish Intercollegiate Guidelines Network (SIGN) and the Scottish Medicines Consortium (SMC) suggestions on using brand-new drugs in the Scottish NHS. In Wales, Local Heath Boards (LHBs) plan, secure and deliver healthcare services in their areas and there are 3 NHS Trusts providing emergency, cancer care and public health services nationally. In Northern Ireland, a single body, the Health and Care Board is supervising commissioning, performance and resource management and improvement of healthcare in the country and six Health and Social Care Trusts provide these services (www.hscni.net). A variety of health agencies support ancillary services and deal with a wide variety of health and care concerns including cancer screening, blood transfusion, public health etc. In Wales Community Health Councils are statutory ordinary bodies promoting the interests of the general public in the health service in their district and in Northern Ireland the Patient and Client Council represent clients, customers and carers.
Predictive, Preventive and Personalised Medicine (PPPM) in the NHS
Like other national health care systems, predictive, preventive and/or customised medicine services within the NHS have generally been provided and are part of illness diagnosis and treatment. Preventive medicine, unlike predictive or personalised medication, is its own recognized entity and pertinent services are directed by Public Health and provided either by means of GP, social work or health centers. Patient-tailored treatment has always prevailed practice for excellent clinicians in the UK and any other health care system. The terms predictive and customised medication though are evolving to describe a far more technologically sophisticated way of diagnosing illness and forecasting action to the requirement of care, in order to increase the advantage for the patient, the public and the health system.
References to predictive and customised medicine are progressively being presented in NHS associated info. The NHS Choices website describes how clients can obtain customised suggestions in relation to their condition, and offers info on predictive blood test for disease such as TB or diabetes. The NIHR through NHS-supported research and together with academic and business working together networks is investing a substantial percentage of its budget plan in verifying predictive and preventive healing interventions [10] The previous federal government thought about the advancement of preventive, people-centred and more efficient health care services as the ways for the NHS to react to the difficulties that all modern-day health care systems are dealing with in the 21st century, particularly, high patient expectation, ageing populations, harnessing of information and technological development, altering workforce and progressing nature of illness [12] Increased focus on quality (patient security, patient experience and medical efficiency) has actually also supported development in early diagnosis and PPPM-enabling technologies such as telemedicine.

A number of preventive services are provided through the NHS either through GP surgical treatments, social work or healthcare facilities depending upon their nature and consist of:
The Cancer Screening programmes in England are nationally coordinated and include Breast, Cervical and Bowel Cancer Screening. There is also an informed choice Prostate Cancer Risk Management program (www.cancerscreening.nhs.uk).
The Child Health Promotion Programme is handling problems from pregnancy and the first 5 years of life and is provided by neighborhood midwifery and health visiting groups [13]
Various immunisation programmes from infancy to adulthood, provided to anyone in the UK totally free and normally provided in GP surgeries.
The Darzi evaluation set out six key medical goals in relation to improving preventive care in the UK consisting of, 1) taking on obesity, 2) lowering alcohol damage, 3) dealing with drug dependency, 4) lowering smoking cigarettes rates, 5) enhancing sexual health and 6) improving psychological health. Preventive programmes to attend to these concerns have actually been in location over the last decades in various types and through various initiatives, and consist of:
Assessment of cardiovascular risk and of people at greater danger of cardiovascular disease is normally preformed through GP surgeries.
Specific preventive programs (e.g. suicide, accident) in local schools and community
Family preparation services and prevention of sexually sent disease programs, often with a focus on youths
A range of prevention and health promo programmes related to lifestyle options are delivered though GPs and neighborhood services including, alcohol and smoking cigarettes cessation programmes, promotion of healthy consuming and exercise. A few of these have a specific focus such as health promotion for older people (e.g. Falls Prevention).
White paper 2010 - Equity and excellence: liberating the NHS

The existing government's 2010 "Equity and excellence: Liberating the NHS" White Paper has set out the vision of the future of an NHS as an organisation that still remains real to its founding principle of, offered to all, complimentary at the point of use and based upon need and not ability to pay. It likewise continues to promote the principles and worths defined in the NHS Constitution. The future NHS is part of the Government's Big Society which is build on social uniformity and entails rights and obligations in accessing cumulative health care and ensuring reliable usage of resources thus delivering much better health. It will provide healthcare results that are among the very best in the world. This vision will be implemented through care and organisation reforms focusing on 4 areas: a) putting clients and public initially, b) enhancing on quality and health outcomes, c) autonomy, accountability and democratic legitimacy, and d) cut administration and improve efficiency [5] This technique refers to issues that pertain to PPPM which suggests the increasing influence of PPPM principles within the NHS.
According to the White Paper the principle of "shared decision-making" (no decision about me without me) will be at the centre of the "putting emphasis on patient and public very first" plans. In reality this consists of plans emphasising the collection and ability to access by clinicians and clients all patient- and treatment-related information. It also includes greater attention to Patient-Reported Outcome Measures, higher choice of treatment and treatment-provider, and significantly customised care planning (a "not one size fits all" approach). A freshly created Public Health Service will combine existing services and place increased focus on research analysis and assessment. Health Watch England, a body within the Care Quality Commission, will provide a more powerful patient and public voice, through a network of local Health Watches (based on the existing Local Involvement Networks - LINks).
The NHS Outcomes Framework sets out the concerns for the NHS. Improving on quality and health outcomes, according to the White Paper, will be attained through modifying goals and healthcare top priorities and establishing targets that are based on scientifically reliable and evidence-based procedures. NICE have a central role in developing recommendations and requirements and will be anticipated to produce 150 brand-new requirements over the next 5 years. The government plans to establish a value-based pricing system for paying pharmaceutical business for supplying drugs to the NHS. A Cancer Drug Fund will be developed in the interim to cover patient treatment.
The abolition of SHAs and PCTs, are being proposed as methods of supplying higher autonomy and responsibility. GP Consortia supported by the NHS Commissioning Board will be accountable for commissioning healthcare services. The introduction of this type of "health management organisations" has actually been somewhat controversial but possibly not totally unexpected [14, 15] The transfer of PCT health improvement function to regional authorities intends to supply increased democratic legitimacy.
Challenges dealing with the UK healthcare system
Overall the health, along with ideological and organisational difficulties that the UK Healthcare system is facing are not different to those faced by numerous nationwide healthcare systems throughout the world. Life expectancy has actually been progressively increasing across the world with occurring increases in persistent illness such as cancer and neurological conditions. Negative environment and way of life influences have actually created a pandemic in obesity and associated conditions such as diabetes and heart disease. In the UK, coronary heart problem, cancer, renal disease, psychological health services for grownups and diabetes cover around 16% of overall National Health Service (NHS) expense, 12% of morbidity and in between 40% and 70% of death [3] Across Western societies, health inequalities are disturbingly increasing, with minority and ethnic groups experiencing most serious diseases, early death and disability. The House of Commons Health Committee alerts that whilst the health of all groups in England is enhancing, over the last ten years health inequalities in between the social classes have widened-the gap has actually increased by 4% for men, and by 11% for women-due to the truth that the health of the abundant is enhancing much quicker than that of the bad [16] The focus and practice of health care services is being changed from typically providing treatment and helpful or palliative care to progressively handling the management of persistent illness and rehab regimes, and providing illness avoidance and health promo interventions. Pay-for-performance, changes in regulation together with cost-effectiveness and spend for medicines problems are becoming a critical factor in new interventions reaching medical practice [17, 18]

Preventive medication is sturdily established within the UK Healthcare System, and predictive and personalised approaches are progressively ending up being so. Implementation of PPPM interventions may be the service but likewise the reason for the health and healthcare difficulties and predicaments that health systems such as the NHS are dealing with [19] The efficient intro of PPPM requires clinical understanding of illness and health, and technological development, together with detailed strategies, evidence-based health policies and appropriate regulation. Critically, education of healthcare professionals, patients and the public is also vital. There is little doubt however that utilizing PPPM properly can help the NHS achieve its vision of delivering health care results that will be among the best in the world.
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