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In PAH, Viagra acts by relaxing blood vessels in the lungs, which allows blood to flow more easily, viagra boys tour helping to reduce the workload on the heart. Over the years, penis enlargement surgery cost in india the use of Viagra has expanded beyond the treatment of ED. It has been studied and occasionally used for other medical conditions, including pulmonary arterial hypertension (PAH) where it is marketed under the brand name Revatio. Viagra, scientifically known as sildenafil citrate, was initially developed as a medication for treating high blood pressure and angina, a type of chest pain associated with heart disease.
Since its approval by the FDA in 1998, Viagra has become one of the most well-known and frequently prescribed drugs for erectile dysfunction worldwide. However, during clinical trials, researchers discovered that it had a profound effect on erectile dysfunction (ED), which led to its repositioning as a treatment for this condition. Erectile dysfunction is a condition where a man is unable to achieve or maintain an erection adequate for satisfactory sexual performance.
The prevalence of ED increases with age and can be influenced by a variety of factors including psychological issues, health conditions like diabetes and heart disease, and certain medications. It is contraindicated in individuals who take nitrates for heart disease, as mentioned, and those with certain health conditions such as severe liver impairment or recent history of stroke or heart attack. Before starting treatment, it's essential for individuals to consult with a healthcare provider to ensure Viagra is a safe option based on their health status and other medications they may be taking.
Despite its benefits, Viagra is not suitable for everyone. Individuals with cardiovascular conditions, particularly those taking nitrate drugs for chest pain, are advised against using Viagra due to the risk of severe blood pressure drops. The drug is generally safe for most men, but it is not devoid of side effects. More serious but rare side effects can include priapism (a painful erection lasting longer than four hours), sudden hearing loss, or vision loss.
Common adverse reactions include headaches, facial flushing, indigestion, nasal congestion, and, less commonly, changes in vision such as increased sensitivity to light or blurred vision. It brought the topic of erectile dysfunction out of the shadows and into open discussion. Moreover, it has been a catalyst for the pharmaceutical industry to invest in further research into sexual health, leading to the development of other similar medications such as Cialis (tadalafil) and Levitra (vardenafil).
The introduction of Viagra also had significant social and cultural impacts. By inhibiting PDE5, Viagra enhances the effect of nitric oxide and cGMP, leading to improved erectile function. This enzyme increases levels of cGMP, leading to smooth muscle relaxation and inflow of blood to the penile tissues, thereby producing an erection. The mechanism by which Viagra operates is through the inhibition of phosphodiesterase-5 (PDE5), an enzyme that promotes the breakdown of cyclic guanosine monophosphate (cGMP).
In the presence of sexual stimulation, nitric oxide is released in the corpus cavernosum, part of the penis, which activates the enzyme guanylate cyclase. Viagra is typically taken in pill form approximately 30 minutes to an hour before sexual activity, and its effects can last for up to four hours. It is important to note that sexual stimulation is required for Viagra to be effective.
Since its approval by the FDA in 1998, Viagra has become one of the most well-known and frequently prescribed drugs for erectile dysfunction worldwide. However, during clinical trials, researchers discovered that it had a profound effect on erectile dysfunction (ED), which led to its repositioning as a treatment for this condition. Erectile dysfunction is a condition where a man is unable to achieve or maintain an erection adequate for satisfactory sexual performance.
The prevalence of ED increases with age and can be influenced by a variety of factors including psychological issues, health conditions like diabetes and heart disease, and certain medications. It is contraindicated in individuals who take nitrates for heart disease, as mentioned, and those with certain health conditions such as severe liver impairment or recent history of stroke or heart attack. Before starting treatment, it's essential for individuals to consult with a healthcare provider to ensure Viagra is a safe option based on their health status and other medications they may be taking.
Despite its benefits, Viagra is not suitable for everyone. Individuals with cardiovascular conditions, particularly those taking nitrate drugs for chest pain, are advised against using Viagra due to the risk of severe blood pressure drops. The drug is generally safe for most men, but it is not devoid of side effects. More serious but rare side effects can include priapism (a painful erection lasting longer than four hours), sudden hearing loss, or vision loss.
Common adverse reactions include headaches, facial flushing, indigestion, nasal congestion, and, less commonly, changes in vision such as increased sensitivity to light or blurred vision. It brought the topic of erectile dysfunction out of the shadows and into open discussion. Moreover, it has been a catalyst for the pharmaceutical industry to invest in further research into sexual health, leading to the development of other similar medications such as Cialis (tadalafil) and Levitra (vardenafil).
The introduction of Viagra also had significant social and cultural impacts. By inhibiting PDE5, Viagra enhances the effect of nitric oxide and cGMP, leading to improved erectile function. This enzyme increases levels of cGMP, leading to smooth muscle relaxation and inflow of blood to the penile tissues, thereby producing an erection. The mechanism by which Viagra operates is through the inhibition of phosphodiesterase-5 (PDE5), an enzyme that promotes the breakdown of cyclic guanosine monophosphate (cGMP).
In the presence of sexual stimulation, nitric oxide is released in the corpus cavernosum, part of the penis, which activates the enzyme guanylate cyclase. Viagra is typically taken in pill form approximately 30 minutes to an hour before sexual activity, and its effects can last for up to four hours. It is important to note that sexual stimulation is required for Viagra to be effective.
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