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작성자 Von Nicolle
댓글 0건 조회 38회 작성일 25-05-03 23:55

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It can stem from both psychological and physiological causes, including diabetes, cardiovascular disease, penis enlargement surgery types hormonal imbalances, and psychological factors such as anxiety or depression. Viagra’s role in treating this condition lies in its effects on blood flow. Erectile dysfunction is a condition where there is a difficulty in achieving or maintaining an erection suitable for sexual intercourse. Viagra works by inhibiting an enzyme known as phosphodiesterase type 5 (PDE5), which is responsible for the breakdown of cGMP in the corpus cavernosum.

By blocking PDE5, Viagra enhances the effects of NO by prolonging the duration and effect of cGMP, thus improving the ability to achieve and maintain an erection in the presence of sexual stimulation. NO activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP). PDE5 breaks down cGMP, thus inhibiting erectile function; Viagra counters this by reducing the activity of PDE5, enhancing erectile response when a man is sexually stimulated.

The primary mechanism by which Viagra operates is through the inhibition of the enzyme phosphodiesterase type 5 (PDE5), which is found predominantly in the corpus cavernosum, the spongy tissue of the penis. Under normal circumstances, upon sexual stimulation, nitric oxide (NO) is released in the corpus cavernosum. cGMP causes the smooth muscles of the corpus cavernosum to relax, leading to an inflow of blood and an erection. Its discovery was somewhat serendipitous; originally developed as a treatment for hypertension and angina pectoris, lisinopril 5 mg for sale researchers noted the drug's ability to induce penile erections as a side effect during clinical trials.

Viagra, known generically as sildenafil citrate, is a medication primarily used to treat erectile dysfunction (ED) in men. Since its market introduction by Pfizer in 1998, Viagra has become one of the most well-known and frequently prescribed drugs for ED. More severe reactions, though rare, can include priapism (a painful erection lasting longer than four hours), sudden hearing loss, and myocardial infarction, especially in those with pre-existing heart conditions.

Despite its benefits, Viagra is not without side effects. The most common include headaches, flushing, indigestion, nasal congestion, and impaired vision. However, it is important to note that an erection will not occur just by taking the pill; sexual stimulation is required for Viagra to work. It should be taken approximately one hour before sexual activity, and its effects can last up to four hours. Viagra is administered orally and is available in 25 mg, 50 mg, and 100 mg doses.

The recommended starting dose is typically 50 mg, doxycycline otc drug adjusted based on effectiveness and toleration. Viagra, chemically known as sildenafil citrate, was first developed by scientists in Britain working for Pfizer in 1989. Originally intended as a treatment for hypertension and angina pectoris, its notable side effect on erectile dysfunction (ED) redirected its course towards sexual health, marking a revolutionary step in its domain. Its availability has opened up conversations about sexual health issues that were previously considered taboo, improving awareness and treatment accessibility.

Viagra's introduction has had a profound impact on sexual health and has helped destigmatize ED.

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